BDBM50482194 CHEMBL1082380

SMILES CC1N(C(C2CC2)c2cn[nH]c2C1=O)S(=O)(=O)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=OFWZIXOHGWMONG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50482194   

TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50482194(CHEMBL1082380)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of gamma-secretase-mediated notch cleavage in human SNC cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed