BDBM50483018 CHEMBL485651

SMILES C#C[C@@]1(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C=C[C@H](n2cc(C)c(=O)[nH]c2=O)O1

InChI Key InChIKey=MDNXEWRQQBRWRA-UHFFFAOYSA-N

Data  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50483018   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483018BDBM50483018(CHEMBL485651)
Affinity DataKd:  1.14E+4nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of HIV 1 reverse transcriptase assessed as incorporation of 4-EdTMP by burst assay using RNA/DNA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483018BDBM50483018(CHEMBL485651)
Affinity DataKd:  1.58E+4nMAssay Description:Inhibition of DNA-dependent DNA polymerase activity of HIV 1 reverse transcriptase assessed as incorporation of 4-EdTMP by burst assay using DNA/DNA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483018BDBM50483018(CHEMBL485651)
Affinity DataKd:  4.34E+4nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of HIV 1 reverse transcriptase M184V mutant assessed as incorporation of 4-EdTMP by burst assay u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483018BDBM50483018(CHEMBL485651)
Affinity DataKd:  1.68E+5nMAssay Description:Inhibition of DNA-dependent DNA polymerase activity of HIV 1 reverse transcriptase M184V mutant assessed as incorporation of 4-EdTMP by burst assay u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed