BDBM50483281 CHEMBL1643429

SMILES COc1ccc(CN2CCCn3c2nnc3-c2ccc(c(OC)c2)-n2cnc(C)c2)cc1

InChI Key InChIKey=LMFRRXSPCPRHFM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50483281   

TargetPresenilin-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50483281(CHEMBL1643429)
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of gamma secretase-mediated amyloid beta42 production in HEK293 cells by sandwich immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed