BDBM50484045 CHEMBL1801257

SMILES N#Cc1cc(Cl)cc(Oc2cc(OCc3n[nH]c(-c4ccncc4)c3Cl)ccc2Cl)c1

InChI Key InChIKey=RURQSSZVFHRLEE-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50484045   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50484045BDBM50484045(CHEMBL1801257)
Affinity DataKi:  0.5nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50484045BDBM50484045(CHEMBL1801257)
Affinity DataKi:  0.5nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant by electrochemiluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50484045BDBM50484045(CHEMBL1801257)
Affinity DataKi:  0.700nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed