BDBM50484096 CHEMBL1814615

SMILES [#6]-[#8]-c1ccc(cc1-[#8])\[#7]=[#6]-1\c2cccc(Cl)c2-[#6](=O)-c2c(Cl)cccc-12

InChI Key InChIKey=OFXIIJHGLSJNFT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50484096   

TargetTubulin beta chain(Pig)
Westphalian Wilhelms-University

Curated by ChEMBL
LigandPNGBDBM50484096(CHEMBL1814615)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of pig brain tubulin polymerization after 30 mins by turbidimetry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Westphalian Wilhelms-University

Curated by ChEMBL
LigandPNGBDBM50484096(CHEMBL1814615)
Affinity DataIC50: 2.60E+3nMAssay Description:Displacement of [3H]colchicine from biotinylated pig brain tubulin after 2 hrs by competitive scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed