BDBM50484641 CHEMBL1823911

SMILES COc1ccc(cc1OC)S(=O)(=O)N(Cc1ccc2OC(C)(C)C=Cc2c1)C(C)C

InChI Key InChIKey=YTQXBXMFEBDFCP-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50484641   

TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Human)
Emory University Csi

Curated by ChEMBL

LigandBDBM50484641(CHEMBL1823911)Copy SMILESCopy InChI

Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of HIF1 transcriptional activity in human LN229 cells expressing VEGF-HRE-V6R and coexpressing luciferase, lac Z gene incubated for 1 hr i...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/29/2020
Entry Details Article
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TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Human)
Emory University Csi

Curated by ChEMBL

LigandBDBM50484641(CHEMBL1823911)Copy SMILESCopy InChI

Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of HIF1 in human LN229 cells after 1 hr preincubation under hypoxic condition measured after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/29/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL