BDBM50484669 CHEMBL1823903

SMILES CC1(C)Oc2ccc(CN(c3ccccc3)S(=O)(=O)c3cc(Cl)ccc3Cl)cc2C=C1

InChI Key InChIKey=BZGNCAPNVBFAKW-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50484669   

TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Human)
Georgia State University

Curated by ChEMBL

LigandBDBM50484669(CHEMBL1823903)Copy SMILESCopy InChI

Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of HIF1 in human LN229 cells after 1 hr preincubation under hypoxic condition measured after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/29/2020
Entry Details Article
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TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Human)
Georgia State University

Curated by ChEMBL

LigandBDBM50484669(CHEMBL1823903)Copy SMILESCopy InChI

Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of HIF1 transcriptional activity in human LN229 cells expressing VEGF-HRE-V6R and coexpressing luciferase, lac Z gene incubated for 1 hr i...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/29/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL