BDBM50484691 CHEMBL1940044

SMILES CCC1(C)Oc2ccc(CN(c3ccccc3)S(=O)(=O)c3ccc(OC)c(OC)c3)cc2C=C1

InChI Key InChIKey=CXMTUTBJHKDAEU-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50484691   

TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Human)
Georgia State University

Curated by ChEMBL

LigandBDBM50484691(CHEMBL1940044)Copy SMILESCopy InChI

Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of HIF1 in human LN229 cells after 1 hr preincubation under hypoxic condition measured after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/29/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL