BDBM50484697 CHEMBL1939068

SMILES CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3[nH]nc(OC)c3c2)c1Cl

InChI Key InChIKey=VPCGBNNYQVEART-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50484697   

TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50484697(CHEMBL1939068)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of full-length B-Raf V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50484697(CHEMBL1939068)
Affinity DataIC50: 19nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human MALME-3M cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed