BDBM50484830 2-Hydroxy-1 Naphthylaldehydeisonicotinoyl Hydrazone::CHEMBL390195

SMILES Oc1ccc2ccccc2c1\C=N\NC(=O)c1ccncc1

InChI Key InChIKey=WQSHHAVECQJKLX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50484830   

TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50484830(2-Hydroxy-1 Naphthylaldehydeisonicotinoyl Hydrazon...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type HIV1 integrase strand transfer activity using 5'-end 32P-labeled linear oligonucleotide as substrate preincubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50484830(2-Hydroxy-1 Naphthylaldehydeisonicotinoyl Hydrazon...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type HIV1 integrase 3'-processing activity using 5'-end 32P-labeled linear oligonucleotide as substrate preincubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Magna Graecia University of Catanzaro

Curated by ChEMBL
LigandPNGBDBM50484830(2-Hydroxy-1 Naphthylaldehydeisonicotinoyl Hydrazon...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ribonuclease H activity of HIV1 reverse transcriptase using as poly(dC)-[3H]poly(rG) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed