BDBM50485093 CHEMBL2030236

SMILES CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3cc(nn3c2)N2CCCC2)c1F

InChI Key InChIKey=BTKJOOFZQTUKKQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50485093   

TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50485093(CHEMBL2030236)
Affinity DataIC50: 367nMAssay Description:Inhibition of full-length B-raf V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50485093(CHEMBL2030236)
Affinity DataIC50: 664nMAssay Description:Inhibition of B-raf V600E mutant-mediated Erk phosphorylation in human Malme3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed