BDBM50485657 CHEMBL2146996

SMILES Cc1c(O)c(=S)ccn1Cc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=GLXWHSSCMFPQGL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50485657   

Target72 kDa type IV collagenase(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50485657(CHEMBL2146996)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MMP-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50485657(CHEMBL2146996)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetElastase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50485657(CHEMBL2146996)
Affinity DataIC50: 2.73E+3nMAssay Description:Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetElastase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50485657(CHEMBL2146996)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa LasB elastase using aminobenzoyl-Ala-Gly-Leu-Ala-p-nitro-benzyl-amide as substrate b microtiter-based fluorimetr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetLethal factor(Bacillus anthracis)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50485657(CHEMBL2146996)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of anthrax lethal factorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetStromelysin-1(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50485657(CHEMBL2146996)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of MMP-3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed