BDBM50485764 CHEMBL2165912

SMILES CC[C@H](C)CN(C[C@H]([C@H](Cc1ccccc1)NC(=O)OCCNC(=O)C(Cl)Cl)O)S(=O)(=O)c2ccc(cc2)OC

InChI Key InChIKey=JJONTVSMJKRGJO-UHFFFAOYSA-N

Data  4 KI

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50485764   

TargetProtease(Human immunodeficiency virus type 1)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50485764(CHEMBL2165912)
Affinity DataKi:  0.00300nMAssay Description:Inhibition of wild type HIV1 protease by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetHIV-1 protease(Human immunodeficiency virus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50485764(CHEMBL2165912)
Affinity DataKi:  0.0440nMAssay Description:Inhibition of HIV1 protease I50V, A71V mutant by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetHIV-1 protease(Human immunodeficiency virus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50485764(CHEMBL2165912)
Affinity DataKi:  0.400nMAssay Description:Inhibition of HIV1 protease L10I, G48V, I54V, L63P and V82A mutant by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetHIV-1 protease(Human immunodeficiency virus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50485764(CHEMBL2165912)
Affinity DataKi:  0.563nMAssay Description:Inhibition of HIV1 protease L10I, L63P, A71V, G73S, I84V, L90M mutant by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed