BDBM50485770 CHEMBL2165898

SMILES CC[C@H](C)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)OCCNC(=O)OC(C)(C)C)S(=O)(=O)c1ccc2ncsc2c1

InChI Key InChIKey=ATGDFHAACSGXGG-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50485770   

TargetProtease(Human immunodeficiency virus type 1)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50485770(CHEMBL2165898)
Affinity DataKi:  0.230nMAssay Description:Inhibition of wild type HIV1 protease by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetHIV-1 protease(Human immunodeficiency virus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50485770(CHEMBL2165898)
Affinity DataKi:  2.5nMAssay Description:Inhibition of HIV1 protease I50V, A71V mutant by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetHIV-1 protease(Human immunodeficiency virus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50485770(CHEMBL2165898)
Affinity DataKi:  3.20nMAssay Description:Inhibition of HIV1 protease L10I, L63P, A71V, G73S, I84V, L90M mutant by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetHIV-1 protease(Human immunodeficiency virus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50485770(CHEMBL2165898)
Affinity DataKi:  4nMAssay Description:Inhibition of HIV1 protease L10I, G48V, I54V, L63P and V82A mutant by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed