BDBM50485977 CHEMBL2180373

SMILES COc1cc(\C=C2/CCCN3[C@@H](CN4CCOCC4)CON=C23)ccc1-n1cnc(C)c1

InChI Key InChIKey=PXTKGOXMNWSPGV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50485977   

TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485977(CHEMBL2180373)
Affinity DataIC50: 3.70E+3nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed