BDBM50486616 CHEMBL2236588

SMILES COc1ccccc1Cn1cc(C(=O)\C=C(/O)C(O)=O)c(=O)c2ccccc12

InChI Key InChIKey=UHKGVUWBDHSDRE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50486616   

TargetIntegrase(Human immunodeficiency virus type 1)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50486616(CHEMBL2236588)
Affinity DataIC50: 38nMAssay Description:Inhibition of HIV-1 integrase assessed as inhibition of strand transfer activity using 32P-labeled DNA as substrate after 1 hr by gel-based assay in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50486616(CHEMBL2236588)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of HIV-1 integrase assessed as inhibition of 3'-processing activity using 32P-labeled DNA as substrate after 1 hr by gel-based assay in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50486616(CHEMBL2236588)
Affinity DataIC50: 4.11E+3nMAssay Description:Inhibition of Human immunodeficiency virus 1 integrase 3'-processing activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetReverse transcriptase(Human immunodeficiency virus type 1)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50486616(CHEMBL2236588)
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of RNase H function of HIV1 reverse transcriptase using DNA/RNA hybrid as substrate by fluorescence spectrometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50486616(CHEMBL2236588)
Affinity DataIC50: 2.63E+4nMAssay Description:Inhibition of Human immunodeficiency virus 1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article