BDBM50487415 CHEMBL2261432

SMILES CC(=O)C1=C(C)N=C(NC1c1ccccc1)SCCC(O)=O

InChI Key InChIKey=UKKLVFSCEPWYNJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50487415   

TargetDihydrofolate reductase(Human)TBA
LigandPNGBDBM50487415(CHEMBL2261432)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of Homo sapiens (human) dihydrofolate reductase using dihydrofolate as substrate incubated for 5 min prior to substrate addition by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

LigandPNGBDBM50487415(CHEMBL2261432)
Affinity DataIC50: 27nMAssay Description:Inhibition of Cryptosporidium parvum recombinant DHFR using dihydrofolate as substrate incubated for 5 min prior to substrate addition by spectrophot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article