BDBM50489305 CHEMBL1643346

SMILES COc1cc(C#CC(=O)O[C@H]2CC[C@@H](N(C)[C@H]3CC[C@@H](OC(=O)c4cc(OC)c(OC)c(OC)c4)CC3)CC2)cc(OC)c1OC

InChI Key InChIKey=TUDPGFIDCKVNGY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50489305   

TargetATP-dependent translocase ABCB1(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50489305BDBM50489305(CHEMBL1643346)
Affinity DataIC50: 70nMAssay Description:Inhibition of P-glycoprotein in human doxorubicin-resistant K562 cells assessed as half maximal increase of pirarubicin accumulation by spectrofluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed