BDBM50490555 CHEMBL2338395

SMILES [H][C@]12CC[C@]([H])(C[C@H](C1)c1nc3c(cnn3c3[nH]ncc13)-c1ccc(nc1)-c1ccccc1)N2C(=O)c1nnc[nH]1

InChI Key InChIKey=XDWRYVRDKJOART-OWZKRDHZSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50490555   

TargetRegulatory-associated protein of mTOR/Serine/threonine-protein kinase mTOR/Target of rapamycin complex subunit LST8(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL

LigandBDBM50490555(CHEMBL2338395)Copy SMILESCopy InChI

Affinity DataIC50:  1nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as reduction in phosphorylated 4E-BP1Thr37/46 level after 90 mins by immunofluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI