BDBM50490672 CHEMBL2336826
SMILES CN(C)CCOc1ccc(cc1)-c1nc(c([nH]1)-c1ccncc1)-c1ccc2c(O)cccc2c1
InChI Key InChIKey=YWRJKORZQLKNOF-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50490672
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant N-terminal His-tagged BRAF V600E mutant expressed in Sf9 cells using GST-tagged MEK1 and ATP as substrate incubated f...More data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Inhibition of BRAF V600E mutant in human WM266.4 cells assessed as inhibition of ERK phosphorylation after 6 hrs by DELFIA assayMore data for this Ligand-Target Pair