BDBM50490935 CHEMBL2348625::d4TTP-4PEG-TMC

SMILES Cc1cc(C#CCOCCOCCOCCOCCOCC#Cc2cn([C@H]3C=C[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O3)c(=O)[nH]c2=O)cc(C)c1Oc1ccnc(Nc2ccc(C#N)cc2)n1

InChI Key InChIKey=ATYKKTVKFKHXRG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50490935   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50490935BDBM50490935(d4TTP-4PEG-TMC | CHEMBL2348625)
Affinity DataIC50: 3nMAssay Description:Competitive inhibition of C-Terminal histidine-tagged wild type heterodimeric HIV-1 reverse transcriptase p66/p51 assessed as inhibition of dTTP inco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50490935BDBM50490935(d4TTP-4PEG-TMC | CHEMBL2348625)
Affinity DataIC50: 42nMAssay Description:Competitive inhibition of C-Terminal histidine-tagged wild type heterodimeric HIV-1 reverse transcriptase p66/p51 assessed as inhibition of dGTP inco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed