BDBM50491387 CHEMBL2380972

SMILES CNC[C@H]1CCC[C@H]1c1ccc2[nH]cc(C#N)c2c1

InChI Key InChIKey=PUIPTRFLVUMEKQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50491387   

TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491387(CHEMBL2380972)
Affinity DataIC50: 64nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491387(CHEMBL2380972)
Affinity DataIC50: 510nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491387(CHEMBL2380972)
Affinity DataIC50: 660nMAssay Description:Displacement of [3H]WIN-35428 form human DAT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed