BDBM50491762 CHEMBL2385963

SMILES Cc1ncc(C#N)c(Nc2ccc(OCc3ccccn3)c(Cl)c2)c1\C=C\c1ccc(CNCCS(C)(=O)=O)o1

InChI Key InChIKey=VCWFAEZKDDTJAN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50491762   

TargetEpidermal growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50491762(CHEMBL2385963)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant EGFR (unknown origin) after 10 mins by DELFIA/time-resolved fluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50491762(CHEMBL2385963)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant ErbB-2 (unknown origin) after 10 mins by DELFIA/time-resolved fluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed