BDBM50491787 CHEMBL2385960

SMILES Cc1ncnc(Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)c1C#Cc1ccc(CNCCS(C)(=O)=O)o1

InChI Key InChIKey=YRXYQXDOPAYQGP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50491787   

TargetEpidermal growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50491787(CHEMBL2385960)
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant EGFR (unknown origin) after 10 mins by DELFIA/time-resolved fluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50491787(CHEMBL2385960)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant ErbB-2 (unknown origin) after 10 mins by DELFIA/time-resolved fluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed