BDBM50492493 CHEMBL2402939

SMILES CN/C1=N/C[C@@H](C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)CN1

InChI Key InChIKey=IRLBHQXMZHCSMJ-UHFFFAOYSA-N

Data  5 KI  6 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50492493   

TargetMu-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492493BDBM50492493(CHEMBL2402939)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor in Wistar rat brain membranes after 45 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492493BDBM50492493(CHEMBL2402939)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor in Wistar rat brain membranes after 45 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492493BDBM50492493(CHEMBL2402939)
Affinity DataIC50: 23nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor in Wistar rat brain membranes after 45 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492493BDBM50492493(CHEMBL2402939)
Affinity DataIC50: 23.4nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor in Wistar rat brain membranes after 45 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492493BDBM50492493(CHEMBL2402939)
Affinity DataIC50: 42nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492493BDBM50492493(CHEMBL2402939)
Affinity DataIC50: 77nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492493BDBM50492493(CHEMBL2402939)
Affinity DataKi:  245nMAssay Description:Displacement of [3H]-DIDI from delta opioid receptor in Wistar rat brain membranes after 45 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492493BDBM50492493(CHEMBL2402939)
Affinity DataKi:  245nMAssay Description:Displacement of [3H]-DIDI from delta opioid receptor in Wistar rat brain membranes after 45 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492493BDBM50492493(CHEMBL2402939)
Affinity DataIC50: 338nMAssay Description:Displacement of [3H]-DIDI from delta opioid receptor in Wistar rat brain membranes after 45 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492493BDBM50492493(CHEMBL2402939)
Affinity DataIC50: 339nMAssay Description:Displacement of [3H]-DIDI from delta opioid receptor in Wistar rat brain membranes after 45 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492493BDBM50492493(CHEMBL2402939)
Affinity DataKi: >500nMAssay Description:Displacement of [3H]-U69,593 from kappa opioid receptor in guinea pig brain membranes after 2 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492493BDBM50492493(CHEMBL2402939)
Affinity DataEC50:  1.59E+3nMAssay Description:Agonist activity at mu opioid receptor in rat brain membranes assessed as stimulation of [35S]GTPgammaS binding after 60 mins in presence of GDPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492493BDBM50492493(CHEMBL2402939)
Affinity DataEC50:  1.59E+3nMAssay Description:Agonist activity at mu opioid receptor in rat brain membranes assessed as stimulation of [35S]GTPgammaS binding after 60 mins in presence of GDPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492493BDBM50492493(CHEMBL2402939)
Affinity DataEC50:  1.59E+3nMAssay Description:Agonist activity at mu opioid receptor in rat brain membranes assessed as stimulation of [35S]GTPgammaS binding after 60 mins in presence of GDPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492493BDBM50492493(CHEMBL2402939)
Affinity DataEC50:  1.62E+3nMAssay Description:Agonist activity at mu opioid receptor in rat brain membranes assessed as stimulation of [35S]GTPgammaS binding after 60 mins in presence of GDPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed