BDBM50492753 CHEMBL2413570

SMILES O=C1N(CCCn2cc(COCc3cn(CCCN4C(=O)c5ccccc5C4=O)nn3)nn2)C(=O)c2ccccc12

InChI Key InChIKey=HIOMQJARFWQBQP-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50492753   

TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50492753(CHEMBL2413570)
Affinity DataKd:  3.5nMAssay Description:Binding affinity to human Hsp90 by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50492753(CHEMBL2413570)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human Hsp90 ATPase activity assessed as inhibition of ATP hydrolysis after 60 mins by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed