BDBM50494200 CHEMBL3086088

SMILES C1CN(CCO1)c1nccnc1Oc1ccc(Nc2nc3ccccc3s2)cc1

InChI Key InChIKey=MCPHJRVZGYLLFS-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50494200   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Amgen

Curated by ChEMBL

LigandBDBM50494200(CHEMBL3086088)Copy SMILESCopy InChI

Affinity DataIC50: 4.30nMAssay Description:Inhibition of human recombinant PDE10A using cAMP as substrate preincubated for 30 mins prior to substrate addition measured after 1 hr by IMAP TR-FR...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/1/2020
Entry Details Article
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