BDBM50494245 CHEMBL3087484

SMILES OC[C@H](O)CCOc1ccc2c(COc3cc(Nc4ccc(F)cc4F)ccc3C2=O)c1

InChI Key InChIKey=IGEIZXSGPWMAKF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50494245   

TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50494245(CHEMBL3087484)
Affinity DataIC50: 21nMAssay Description:Competitive inhibition of p38alpha MAP kinase (unknown origin) in presence of 100 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50494245(CHEMBL3087484)
Affinity DataIC50: 3.79E+4nMAssay Description:Inhibition of p38alpha MAP kinase in human whole blood assessed as inhibition of LPS-induced TNFalpha release by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed