BDBM50494248 CHEMBL3086700

SMILES Fc1ccc(Nc2ccc3c(OCc4cc(OCCN5CCOCC5)ccc4C3=O)c2)c(F)c1

InChI Key InChIKey=AXQNARIBQLNAKA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50494248   

TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50494248(CHEMBL3086700)
Affinity DataIC50: 33nMAssay Description:Competitive inhibition of p38alpha MAP kinase (unknown origin) in presence of 100 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50494248(CHEMBL3086700)
Affinity DataIC50: 7.18E+4nMAssay Description:Inhibition of p38alpha MAP kinase in human whole blood assessed as inhibition of LPS-induced TNFalpha release by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed