BDBM50494303 CHEMBL3086703

SMILES C[C@H](NC(=O)c1c(C)cc(cc1C)-c1cccc(N[C@H](C)c2ccc(Cl)c(C)c2)c1)C(O)=O

InChI Key InChIKey=KYHUARFFBDLROH-UHFFFAOYSA-N

Data  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50494303   

TargetSphingosine 1-phosphate receptor 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50494303(CHEMBL3086703)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human S1P1 receptor expressed in CHO cells after 120 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50494303(CHEMBL3086703)
Affinity DataEC50:  245nMAssay Description:Agonist activity at S1P4 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50494303(CHEMBL3086703)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human S1P3 receptor expressed in CHO cells assessed as inhibition of agonist-induced calcium mobilization preincubated for 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50494303(CHEMBL3086703)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human S1P4 receptor expressed in CHO cells assessed as inhibition of agonist-induced calcium mobilization preincubated for 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50494303(CHEMBL3086703)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human S1P5 receptor expressed in CHO cells after 120 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50494303(CHEMBL3086703)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human S1P2 receptor expressed in CHO cells assessed as inhibition of agonist-induced calcium mobilization preincubated for 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed