BDBM50494961 CHEMBL3099428::US10570077, Compound 11

SMILES [H][C@@]12CC=C([C@@H](C)CCO)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3CC[C@@]21[H]

InChI Key InChIKey=TTWLNSHTBPTSHV-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50494961   

TargetEstrogen receptor(Human)
Marquette University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50494961BDBM50494961(CHEMBL3099428 | US10570077, Compound 11)
Affinity DataKd:  320nMAssay Description:Displacement of FITC-estradiol from human ERalpha by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Marquette University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50494961BDBM50494961(CHEMBL3099428 | US10570077, Compound 11)
Affinity DataKd:  320nMAssay Description:Twelve compounds from Schemes 1 and 2 were screened using fluorescence polarization, for their ability to bind ERα (Table 1). Only six compounds...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent