BDBM50495334 CHEMBL3109647

SMILES OC(=O)[C@H]1CC[C@H](Cn2c(=O)n(Cc3cccc(c3C#N)C(F)(F)F)c3ccccc3c2=O)CC1

InChI Key InChIKey=WSTUZGSSQNKRSR-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50495334   

TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50495334(CHEMBL3109647)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human TNKS1 after 1 to 2 hrs by fluorescence polarization methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50495334(CHEMBL3109647)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human TNKS1 incubated for 1 to 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50495334(CHEMBL3109647)
Affinity DataIC50: 20nMAssay Description:Inhibition of human TNKS2 incubated for 30 mins prior to substrate addition measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50495334(CHEMBL3109647)
Affinity DataIC50: 32nMAssay Description:Inhibition of human TNKS1 incubated for 30 mins prior to substrate addition measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50495334(CHEMBL3109647)
Affinity DataIC50: 79nMAssay Description:Inhibition of human TNKS2 incubated for 1 to 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50495334(CHEMBL3109647)
Affinity DataIC50: 79nMAssay Description:Inhibition of human TNKS2 after 1 to 2 hrs by fluorescence polarization methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed