BDBM50495729 CHEMBL3113937

SMILES [O-][n+]1cc(Cl)c(C[C@H](OC(=O)c2ccccc2)c2ccc(OC(F)F)c(OCC3CC3)c2)c(Cl)c1

InChI Key InChIKey=MQQMKMLATGRCEW-QFIPXVFZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50495729   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50495729(CHEMBL3113937)
Affinity DataIC50:  0.0720nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50495729(CHEMBL3113937)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed