BDBM50495829 CHEMBL3112972

SMILES FC(F)(F)c1cc(cc(c1)C(F)(F)F)-c1ccc(COC(=O)Nc2ccccc2)o1

InChI Key InChIKey=NERLGZQWNOXNCL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50495829   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Yale University

Curated by ChEMBL
LigandPNGBDBM50495829(CHEMBL3112972)
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of Toxoplasma gondii TS-DHFR using methylenetetrahydrofolate/dUMP as sustrate preincubated for 10 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Yale University

Curated by ChEMBL
LigandPNGBDBM50495829(CHEMBL3112972)
Affinity DataIC50: 1.90E+5nMAssay Description:Inhibition of Toxoplasma gondii TS-DHFR using methylenetetrahydrofolate/dUMP as sustrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed