BDBM50496278 CHEMBL3127706

SMILES O=C(C1CC11CCN(CC1)C1CCC1)N1CCN(CC1)C1CCOCC1

InChI Key InChIKey=PTCXZEFMBLDAIK-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50496278   

TargetHistamine H3 receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50496278(CHEMBL3127706)
Affinity DataIC50: 66nMAssay Description:Antagonist activity at human histamine H3 receptor long form expressed in CHOK1 cells assessed as inhibition of R-alpha-methylhistamine-induced [35S]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50496278(CHEMBL3127706)
Affinity DataKi:  67nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human histamine H3 receptor expressed in CHOK1 cells after 1.5 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed