BDBM50496535 CHEMBL3126808

SMILES NNC(=O)c1cn(nc1-c1ccc(F)cc1)-c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=GCUBRELAXSZALZ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50496535   

TargetCarbonic anhydrase 9(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50496535(CHEMBL3126808)
Affinity DataKi:  5.5nMAssay Description:Inhibition of human carbonic anhydrase 9-mediated CO2 hydration preincubated for 10 mins by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50496535(CHEMBL3126808)
Affinity DataKi:  8.90nMAssay Description:Inhibition of human carbonic anhydrase 12-mediated CO2 hydration preincubated for 10 mins by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50496535(CHEMBL3126808)
Affinity DataKi:  36nMAssay Description:Inhibition of human carbonic anhydrase 1-mediated CO2 hydration preincubated for 10 mins by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50496535(CHEMBL3126808)
Affinity DataKi:  64nMAssay Description:Inhibition of human carbonic anhydrase 2-mediated CO2 hydration preincubated for 10 mins by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed