BDBM50496555 CHEMBL3127462

SMILES COc1cc2occc2c(OC)c1-c1cc(-c2ccc(cc2)C(F)(F)F)n(n1)-c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=RTDWEGLAYPOTJQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50496555   

TargetProstaglandin G/H synthase 2(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50496555(CHEMBL3127462)
Affinity DataIC50: 340nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate incubated for 10 mins prior to substrate addition measured after 2 mins by e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50496555(CHEMBL3127462)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate incubated for 10 mins prior to substrate addition measured after 2 mins by enzyme immuno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed