BDBM50497560 CHEMBL3344071

SMILES Cc1ccc(-c2nc3c(sc4ccccc43)c(=O)[nH]2)cc1

InChI Key InChIKey=FOFNXWJHZNRHCH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50497560   

TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Perugia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50497560BDBM50497560(CHEMBL3344071)
Affinity DataIC50: 19nMAssay Description:Inhibition of GST-tagged human recombinant TNKS1 incubated for 1 hr using NAD+, biotinylated NAD+ and activated DNA by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Perugia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50497560BDBM50497560(CHEMBL3344071)
Affinity DataIC50: 80nMAssay Description:Inhibition of GST-tagged human recombinant TNKS2 incubated for 1 hr using NAD+, biotinylated NAD+ and activated DNA by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed