BDBM50497870 CHEMBL3323332

SMILES Oc1ccccc1C1=NN(C(C1)c1cc(F)c(O)c(F)c1)c1cccc(Cl)c1

InChI Key InChIKey=CSCSBBSQLJHGCJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50497870   

TargetProtein kinase C zeta type(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50497870(CHEMBL3323332)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PKCzeta in human U937 cells assessed as inhibition of TNFalpha-induced NF-kappaB activation by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetProtein kinase C zeta type(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50497870(CHEMBL3323332)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of human PKCzeta assessed as phosphorylation reaction after 4 mins incubation by cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed