BDBM50497872 CHEMBL3323314

SMILES CC(C)(C)C1=NN(C(C1)c1ccc(O)cc1)c1ccc(Cl)cc1

InChI Key InChIKey=VTWBWUXJZYSPKK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50497872   

TargetProtein kinase C zeta type(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50497872(CHEMBL3323314)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of PKCzeta in human U937 cells assessed as inhibition of TNFalpha-induced NF-kappaB activation by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50497872(CHEMBL3323314)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of iNOS induction in mouse RAW264.7 cells assessed as NO productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetProtein kinase C zeta type(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50497872(CHEMBL3323314)
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of human PKCzeta assessed as phosphorylation reaction after 4 mins incubation by cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetProtein kinase C zeta type(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50497872(CHEMBL3323314)
Affinity DataIC50: 2.67E+4nMAssay Description:Inhibition of PKCzeta val297leu mutant (unknown origin) assessed as phosphorylation reaction after 4 mins incubation by cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed