BDBM50497873 CHEMBL3323343

SMILES Oc1ccc(cc1)C1CC(=NN1c1ccc(Br)cc1)c1cccs1

InChI Key InChIKey=UMLLXYBGJNMIJH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50497873   

TargetProtein kinase C zeta type(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50497873(CHEMBL3323343)
Affinity DataIC50: 500nMAssay Description:Inhibition of human PKCzeta assessed as phosphorylation reaction after 4 mins incubation by cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetProtein kinase C zeta type(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50497873(CHEMBL3323343)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PKCzeta val297leu mutant (unknown origin) assessed as phosphorylation reaction after 4 mins incubation by cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50497873(CHEMBL3323343)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of iNOS induction in mouse RAW264.7 cells assessed as NO productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed