BDBM50497875 CHEMBL3323344

SMILES Oc1ccc(cc1)C1CC(=NN1c1ccc(cc1)C(F)(F)F)c1cccs1

InChI Key InChIKey=QUXYAWGELQKXGX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50497875   

TargetProtein kinase C zeta type(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50497875(CHEMBL3323344)
Affinity DataIC50: 400nMAssay Description:Inhibition of human PKCzeta assessed as phosphorylation reaction after 4 mins incubation by cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50497875(CHEMBL3323344)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of iNOS induction in mouse RAW264.7 cells assessed as NO productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetProtein kinase C zeta type(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50497875(CHEMBL3323344)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of PKCzeta in human U937 cells assessed as inhibition of TNFalpha-induced NF-kappaB activation by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed