BDBM50497881 CHEMBL3323334

SMILES CC(C)(C)C1=NN(C(C1)c1ccc(O)cc1)c1ccc(F)c(F)c1F

InChI Key InChIKey=RDAIYPYLHQHYKX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50497881   

TargetProtein kinase C zeta type(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50497881(CHEMBL3323334)
Affinity DataIC50: 700nMAssay Description:Inhibition of human PKCzeta assessed as phosphorylation reaction after 4 mins incubation by cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetProtein kinase C zeta type(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50497881(CHEMBL3323334)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of PKCzeta in human U937 cells assessed as inhibition of TNFalpha-induced NF-kappaB activation by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed