BDBM50498398 CHEMBL2270111

SMILES OC(=O)c1ccc2[n+]([O-])onc2c1

InChI Key InChIKey=AXRCJZJVVZUOHN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50498398   

TargetCarbonic anhydrase 12(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50498398(CHEMBL2270111)
Affinity DataKi:  995nMAssay Description:Inhibition of human recombinant CA12 by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50498398(CHEMBL2270111)
Affinity DataKi:  2.65E+3nMAssay Description:Inhibition of human recombinant CA9 by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50498398(CHEMBL2270111)
Affinity DataKi:  8.73E+3nMAssay Description:Inhibition of human recombinant CA2 by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50498398(CHEMBL2270111)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human recombinant CA1 by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50498398(CHEMBL2270111)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of HDAC1/2 in human HeLa cells using Boc-Lys (acetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed