BDBM50498573 CHEMBL3609620

SMILES C[C@@H](NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=ZGKMSCDQIDVSIK-FNFCYJGBSA-N

Data  4 KI  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50498573   

TargetSubstance-P receptor(Homo sapiens (Human))
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50498573(CHEMBL3609620)
Affinity DataKi:  0.0160nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor transfected in CHO cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Rattus norvegicus (rat))
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50498573(CHEMBL3609620)
Affinity DataKi:  0.280nMAssay Description:Displacement of [3H]-substance P from rat NK1 receptor transfected in CHO cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50498573(CHEMBL3609620)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]-DAMGO from rat mu opioid receptor transfected in HN9.10 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50498573(CHEMBL3609620)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]-DPDPE from human delta opioid receptor transfected in HN9.10 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50498573(CHEMBL3609620)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at rat mu opioid receptor transfected in HN9.10 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50498573(CHEMBL3609620)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human delta opioid receptor transfected in HN9.10 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50498573(CHEMBL3609620)
Affinity DataIC50:  400nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed