BDBM50498674 CHEMBL3621874

SMILES OC(=O)c1ccnc(c1)-c1cn(nn1)C1CCN(C1)C(=O)CCc1ccccc1

InChI Key InChIKey=BMDGMELYSLPYAP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50498674   

TargetLysine-specific demethylase 5C(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50498674(CHEMBL3621874)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of KDM5C (unknown origin) using H3(1-21)K4Me3-GGK-biotin substrate incubated for 20 mins by alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetLysine-specific demethylase 4C(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50498674(CHEMBL3621874)
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of KDM4C (unknown origin) using H3(1-21)K9Me3-GGK-biotin substrate incubated for 15 mins by alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetLysine-specific demethylase 6B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50498674(CHEMBL3621874)
Affinity DataIC50: 7.94E+4nMAssay Description:Inhibition of KDM6B (unknown origin) using H3(21-44)K27Me3-GK-biotin substrate incubated for 5 mins by alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50498674(CHEMBL3621874)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of KDM4E (unknown origin) by alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetLysine-specific demethylase 3A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50498674(CHEMBL3621874)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of KDM3A (unknown origin) using H3(1-21)K9Me2-GGK-biotin substrate incubated for 5 mins by alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed