BDBM50499076 CHEMBL3735979

SMILES Fc1ccc(Cc2n[nH]c(=O)c3ccccc23)cc1C(=O)N1CCN(CC1)C(=O)c1ccc(I)cc1

InChI Key InChIKey=QOCIPUHZHXLQMK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50499076   

TargetPoly [ADP-ribose] polymerase 1(Human)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50499076(CHEMBL3735979)
Affinity DataIC50:  7nMAssay Description:Inhibition of PARP1 in human G7 cells incubated for 60 mins by immunofluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50499076(CHEMBL3735979)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 10 mins using biotinylated NAD+ and activated DNA by colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50499076(CHEMBL3735979)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of PARP1 in human T98G cells incubated for 60 mins by immunofluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed