BDBM50499216 CHEMBL3736345

SMILES CC(C)(C)n1nnc2CC(CCc12)n1cnc(n1)-c1ccc(F)cc1

InChI Key InChIKey=GOFBHAFTRPSQBA-UHFFFAOYSA-N

Data  1 IC50  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50499216   

TargetMetabotropic glutamate receptor 5(Human)
Eisai

Curated by ChEMBL

LigandBDBM50499216(CHEMBL3736345)Copy SMILESCopy InChI

Affinity DataEC50:  50nMAssay Description:Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/4/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Eisai

Curated by ChEMBL

LigandBDBM50499216(CHEMBL3736345)Copy SMILESCopy InChI

Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/4/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL