BDBM50499253 CHEMBL3735496

SMILES Cc1ccc(S(=O)(=O)N2CCC3=Cc4c(cnn4-c4ccc(F)cc4)C[C@]3(C(=O)c3ccccn3)C2)cc1

InChI Key InChIKey=BWJSGTSHQSLHEA-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50499253   

TargetGlucocorticoid receptor(Human)
Corcept Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50499253BDBM50499253(CHEMBL3735496)
Affinity DataKi:  0.220nMAssay Description:Binding affinity to human recombinant glucocorticoid receptor by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Corcept Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50499253BDBM50499253(CHEMBL3735496)
Affinity DataKi:  4.5nMAssay Description:Antagonist activity at glucocorticoid receptor in human HepG2 cells assessed as inhibition of glucocorticoid-induced TAT activity after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed