BDBM50499256 CHEMBL3736390

SMILES O=C(c1ccco1)[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(S(=O)(=O)c1ccc(C(F)(F)F)cc1)C2

InChI Key InChIKey=RKYSVHVGDAGNFR-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50499256   

TargetGlucocorticoid receptor(Human)
Corcept Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50499256BDBM50499256(CHEMBL3736390)
Affinity DataKi:  0.170nMAssay Description:Binding affinity to human recombinant glucocorticoid receptor by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Corcept Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50499256BDBM50499256(CHEMBL3736390)
Affinity DataKi:  31nMAssay Description:Antagonist activity at glucocorticoid receptor in human HepG2 cells assessed as inhibition of glucocorticoid-induced TAT activity after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed